Search results for "Mental Models"
showing 10 items of 21 documents
Approaching Sex Differences in Cardiovascular Non-Coding RNA Research
2020
International audience; Cardiovascular disease (CVD) is the biggest cause of sickness and mortality worldwide in both males and females. Clinical statistics demonstrate clear sex differences in risk, prevalence, mortality rates, and response to treatment for different entities of CVD. The reason for this remains poorly understood. Non-coding RNAs (ncRNAs) are emerging as key mediators and biomarkers of CVD. Similarly, current knowledge on differential regulation, expression, and pathology-associated function of ncRNAs between sexes is minimal. Here, we provide a state-of-the-art overview of what is known on sex differences in ncRNA research in CVD as well as discussing the contributing biol…
A deterministic model for highly contagious diseases: The case of varicella
2016
[EN] The classic nonlinear Kermack-McKendrick model based upon a system of differential equations has been widely applied to model the rise and fall of global pandemic and also seasonal epidemic by introducing a forced harmonic infectivity which would change throughout the year. These methods work well in their respective domains of applicability, and for certain diseases, but they fail when both seasonality and high infectivity are combined. In this paper we consider a Susceptible-Infected-Recovered, or SIR, model with two latent states to model the propagation and evolutionary history of varicella in humans. We show that infectivity can be calculated from real data and we find a nonstanda…
A conceptual model of feedback mechanisms in adjusted affordances – Insights from usage of a mental mobile health application
2023
Affordance theory provides one of the most prominent lenses through which the socio-technical aspects of a system’s use can be investigated and understood. In this context, the literature has proposed that perceived and actualized affordances may be adjusted over time. Yet, how the adjustment of affordances occurs has not been explained in detail. Thus, in this article, we develop a conceptual model of feedback mechanisms that includes a more explicit description of how affordances are perceived by users, whether actualized and adjusted. With the model, we introduce the central concept of a generative base, out of which affordance perceptions emerge and which can be updated through affordan…
The dual nature of design management
2018
Design management profession has probably got the least attention in the construction industry. One reason could be the lack of explicit conceptualizations about its nature, subject matter and principles. In this article, a conceptual design management framework is proposed on the premise that design management is the management of a structured system of object and subject-oriented, technical and social design activities. Additionally, an example of a mediating visual model is proposed to facilitate the discussions about design activities and design management in academia and practice. The two major premises of this research are 1) as design management is the management of design activity, …
Play together, think alike: Shared mental models in expert music improvisers
2015
International audience; When musicians improvise together, they tend to agree beforehand on a common structure (e.g. a jazz standard) which helps them coordinate. However, in the particular case of collective free improvisation (CFI), musicians deliberately avoid having such a referent. How, then, can they coordinate? We propose that CFI musicians who have experience playing together come to share higher-level knowledge, which is not piece-specific but rather task-specific: an implicit mental model of what it is to improvise freely. We tested this hypothesis on a group of 19 expert improvisers from the Parisian CFI community, who had various degrees of experience playing with one another. D…
Reconsidering Some Aspects of Inquiry Based Science Education: A Case Study on Model Based Inquiry
2014
Neuroprotection by erythropoietin administration after experimental traumatic brain injury.
2007
A large body of evidence indicates that the hormone erythropoietin (EPO) exerts beneficial effects in the central nervous system (CNS). To date, EPO's effect has been assessed in several experimental models of brain and spinal cord injury. This study was conducted to validate whether treatment with recombinant human EPO (rHuEPO) would limit the extent of injury following experimental TBI. Experimental TBI was induced in rats by a cryogenic injury model. rHuEPO or placebo was injected intraperitoneally immediately after the injury and then every 8 h until 2 or 14 days. Forty-eight hours after injury brain water content, an indicator of brain edema, was measured with the wet-dry method and bl…
Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain
2009
Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…
Signalling Three-Way Intersections: Is Redundancy Better Than Only Mandatory or Prohibitory Signs?
2021
This work was supported by the Spanish Government, Ministry of Economy and Competitiveness (PGC2018-095868-B-I00).
Eight Questions for the Speakers
2019
In this paper, we raise a few questions for Bartosz Brozek, Monica Bucciarelli and Philip Johnson-Laird. The questions we ask to Bucciarelli and Johnson-Laird concern the nature of the “sense of correctness” which is at the heart of our normative judgments and reasoning, and the status of the laws of logic relating to mental models. Our questions to Brozek concern the distinction he traces between rudimentary and abstract rules, the role of language in normative behaviour, and the role of mental simulation in the understanding of abstract rules.